个人简历

2011年9月–2015年7月，北京大学化学与分子工程学院化学专业学习，获学士学位；

2015年9月–2021年6月，北京大学化学与分子工程学院无机化学专业学习，硕博连读，获博士学位；

2021年12月–至今，合肥工业大学化学与化工学院，讲师。

主要研究领域、方向

基于金属配合物的新型小分子荧光探针和金属药物的设计合成、性质及机制研究以及探索它们在生物医学领域的应用和临床转化

研究成果（代表性成果）

围绕新型小分子金属配合物荧光探针和金属药物进行研究，近年来已在包括Angew. Chem. Int. Ed., Chem. Sci., Chem. Commun.,Eur. J. Inorg. Chem.在内的国际重要学术期刊上发表SCI学术论文十余篇。

目前承担科研项目

获奖及专利情况

获批专利：

1. Junlong Zhang,Haoyan Yin, Bingwu Wang, Main-group metal complex with cancer cell killing ability and preparation and application thereof,2019,PatentWO 2019214691

著作论文（代表作）

1.Hao-Yan Yin⁺, Jiu-Jiao Gao⁺, Xuemin Chen⁺, Bin Ma⁺, Zi-Shu Yang, Juan Tang, Bing-Wu Wang, Tianfeng Chen, Chu Wang, Song Gao, Jun-Long Zhang*, A Gallium(III) Complex that Engages Protein Disulfide Isomerase A3 (PDIA3) as an Anticancer Target,Angew. Chem. Int. Ed.,2020, 59, 20147-20153 (⁺: These authors contributed equally to this work).

2.Hao-Yan Yin, Jing Lai, Juan Tang, Yanli Shang*, and Jun-Long Zhang*, A cryptand-type aluminum tris(salophen) complex: synthesis, characterization, and cell imaging application,Inorganics,2018, 6, 20;

3.Hao-Yan Yin, Juan Tang, Jun-Long Zhang*, Sulfur speciation defined subcellular localization of coumarin derivatives: Correlation of structural relationship to biological behaviors,Chin. Chem. Lett.,2018, 29, 267-270.

4.Hao-Yan Yin, Juan Tang, Jun-Long Zhang*, Luminescent metal salen complex as intracellular microviscosity fluorescent sensor,Sci. Sin. Chim.,2017, 47, 267.

5.Hao-Yan Yin, Juan Tang, Jun-Long Zhang*, Introducing Metallosalens to Biological Studies: The Renaissance of Traditional Coordination Complexes,Eur. J. Inorg. Chem.,2017, 44, 5085-5093.

6. Juan Tang,Hao-Yan Yinand Jun-Long Zhang*, A luminescent aluminium salen complex allows for monitoring dynamic vesicle trafficking from the Golgi apparatus to lysosomes in living cells,Chem. Sci.,2018, 9, 1931-1939.

7. Juan Tang,Hao-Yan Yinand Jun-Long Zhang*, Luminescent Zinc Complexes as Bioprobes for Imaging Molecular Events in Live Cells,Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells, Elsevier press,2017.